KEGG   Homo sapiens (human): 8698
Entry
8698              CDS       T01001                                 
Symbol
S1PR4, EDG6, LPC1, S1P4, SLP4
Name
(RefSeq) sphingosine-1-phosphate receptor 4
  KO
K04293  sphingosine 1-phosphate receptor 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04068  FoxO signaling pathway
hsa04071  Sphingolipid signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Amiselimod (DG02399): D10904 D10905
Etrasimod (DG02444): D10930 D10931<US>
Ozanimod (DG02827): D10967<US> D10968
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    8698 (S1PR4)
   04071 Sphingolipid signaling pathway
    8698 (S1PR4)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    8698 (S1PR4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    8698 (S1PR4)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Lipid
   Sphingolipid
    8698 (S1PR4)
SSDB
Motif
Pfam: 7tm_1 7tm_4
Other DBs
NCBI-GeneID: 8698
NCBI-ProteinID: NP_003766
OMIM: 603751
HGNC: 3170
Ensembl: ENSG00000125910
UniProt: O95977
Structure
Position
19:3178769..3180332
AA seq 384 aa
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
NT seq 1155 nt   +upstreamnt  +downstreamnt
atgaacgccacggggaccccggtggcccccgagtcctgccaacagctggcggccggcggg
cacagccggctcattgttctgcactacaaccactcgggccggctggccgggcgcgggggg
ccggaggatggcggcctgggggccctgcgggggctgtcggtggccgccagctgcctggtg
gtgctggagaacttgctggtgctggcggccatcaccagccacatgcggtcgcgacgctgg
gtctactattgcctggtgaacatcacgctgagtgacctgctcacgggcgcggcctacctg
gccaacgtgctgctgtcgggggcccgcaccttccgtctggcgcccgcccagtggttccta
cgggagggcctgctcttcaccgccctggccgcctccaccttcagcctgctcttcactgca
ggggagcgctttgccaccatggtgcggccggtggccgagagcggggccaccaagaccagc
cgcgtctacggcttcatcggcctctgctggctgctggccgcgctgctggggatgctgcct
ttgctgggctggaactgcctgtgcgcctttgaccgctgctccagccttctgcccctctac
tccaagcgctacatcctcttctgcctggtgatcttcgccggcgtcctggccaccatcatg
ggcctctatggggccatcttccgcctggtgcaggccagcgggcagaaggccccacgccca
gcggcccgccgcaaggcccgccgcctgctgaagacggtgctgatgatcctgctggccttc
ctggtgtgctggggcccactcttcgggctgctgctggccgacgtctttggctccaacctc
tgggcccaggagtacctgcggggcatggactggatcctggccctggccgtcctcaactcg
gcggtcaaccccatcatctactccttccgcagcagggaggtgtgcagagccgtgctcagc
ttcctctgctgcgggtgtctccggctgggcatgcgagggcccggggactgcctggcccgg
gccgtcgaggctcactccggagcttccaccaccgacagctctctgaggccaagggacagc
tttcgcggctcccgctcgctcagctttcggatgcgggagcccctgtccagcatctccagc
gtgcggagcatctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (36)   

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